If I do not work with SNP detection, can I just translate the colorspace to basespace, then do the mapping? One thing concerning me is that a single mismatch in colorspace not only affects the particular base, but also affects all the downstream bases. So the single mismatch in colorspace is likely to be misalignment in basespace. Does this mean more false positive for colorspace mapping?
What is the advantage for mapping in colorspace for no SNP detection projects?
Any suggestions and comments?
Many thanks
What is the advantage for mapping in colorspace for no SNP detection projects?
Any suggestions and comments?
Many thanks
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