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  • kwatts59
    Member
    • Apr 2011
    • 46

    Is the geneom GRCh37/hg19 from a single person?

    Sorry to ask such novice questions.
    Is the GRCh37/hg19 genome the genome of a single individual, or the composite of multiple people?

    What is the difference between GRCh37/hg19 and GRCh36/hg18? Are they from two different people? If they are, where can I get an electronic copy of the differences between the two individuals?

    Thanks in advance.
  • lh3
    Senior Member
    • Feb 2008
    • 686

    #2
    No, they are mainly from around 6 BAC libraries (six people; well around 6). Over half from an African-American. You can find the location and library information of each BAC used in the assembly from NCBI/UCSC.

    Comment

    • Groningen
      Junior Member
      • Feb 2012
      • 3

      #3
      hg19 or hg18 are different built.depend on what method, what kind of kit and what bioinformatics method you have applied to have a sequence data from one person, you will have his/her sequence data in hg19 or hg18.
      That means one person can have both hg19 or hg18.
      If you have hg18 you can convert it into hg19 or vice versa.

      Comment

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