Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • meetasunil
    Junior Member
    • Sep 2011
    • 2

    #1

    Sock::connect error with blast_formatter 2.2.28+

    Hello,
    I've been getting the following error with the latest as well as older versions of blast+, specifically with the blast_formatter command:

    Error: (311.22) SOCK#1000[?]: [SOCK::Connect] Failed SOCK_gethostbyname("www.ncbi.nlm.nih.gov")
    Error: (303.7) [URL_Connect] Failed to connect to www.ncbi.nlm.nih.gov:80: Unknown

    I'm just using the standalone version and do not understand the need for blast_formatter to try to connect to the ncbi server. The command-line that I use with blast_formatter is as exemplified below:

    blast_formatter -archive file.ASN.1 -outfmt 0 -out file.aln

    It has worked properly before but one fine day I start getting this error..
    Can anyone please help? It's a little urgent for me.


    Thanks and regards,
    Meeta
    India
  • cjfields
    Junior Member
    • Sep 2009
    • 6

    #2
    I had the same problem using a local database. The problem appears to be that blast_formatter looks for the database locally first using the path given for the database in the BLAST run; if it isn't found, then it tries remotely (and of course won't find it if there is no network or the DB is custom).

    In my situation, I had given it a relative path with output redirected to a different folder, so when I attempted to use blast_formatter from that folder, the database couldn't be found using the relative path. I simply moved the data back to where I ran the initial BLAST calls (relative path matched the database location) and got it working. The immediate solution to avoid this altogether is to always use an absolute path when running local BLAST.

    Originally posted by meetasunil View Post
    Hello,
    I've been getting the following error with the latest as well as older versions of blast+, specifically with the blast_formatter command:

    Error: (311.22) SOCK#1000[?]: [SOCK::Connect] Failed SOCK_gethostbyname("www.ncbi.nlm.nih.gov")
    Error: (303.7) [URL_Connect] Failed to connect to www.ncbi.nlm.nih.gov:80: Unknown

    I'm just using the standalone version and do not understand the need for blast_formatter to try to connect to the ncbi server. The command-line that I use with blast_formatter is as exemplified below:

    blast_formatter -archive file.ASN.1 -outfmt 0 -out file.aln

    It has worked properly before but one fine day I start getting this error..
    Can anyone please help? It's a little urgent for me.


    Thanks and regards,
    Meeta
    India

    Comment

    Latest Articles

    Collapse

    • SEQadmin2
      Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
      by SEQadmin2



      CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

      Despite this, “CRISPR helped turn genome editing from a specialized technique into
      ...
      07-31-2026, 11:01 AM
    • SEQadmin2
      Proteomic Platforms: How to Choose the Right Analytical Strategy to Improve Detection and Clinical Applications
      by SEQadmin2


      Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.

      The systematic characterization of the human proteome has
      ...
      07-20-2026, 11:48 AM

    ad_right_rmr

    Collapse

    News

    Collapse

    Topics Statistics Last Post
    Started by SEQadmin2, 08-06-2026, 07:41 AM
    0 responses
    23 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 08-03-2026, 10:13 AM
    0 responses
    35 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 07-31-2026, 02:55 AM
    0 responses
    43 views
    0 reactions
    Last Post SEQadmin2  
    Started by SEQadmin2, 07-24-2026, 12:17 PM
    0 responses
    26 views
    0 reactions
    Last Post SEQadmin2  
    Working...