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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,182 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by crazyhottommy, 07-31-2024, 06:32 AM
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53 views
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Started by crazyhottommy, 07-30-2024, 12:39 PM
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57 views
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Started by cartzo, 04-22-2020, 06:40 AM
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5 responses
2,365 views
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Started by crazyhottommy, 07-28-2024, 09:32 AM
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97 views
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Started by tracecakes, 07-25-2024, 04:01 PM
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173 views
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by tracecakes
07-25-2024, 04:01 PM
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Started by Viola_86, 07-24-2024, 01:18 AM
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85 views
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by Viola_86
07-24-2024, 01:18 AM
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Is it possible to have a mitochondrial genome of size 30-40kbp in insects? Assembled mitogenome which is 32kb in size
by meeranhussain
Started by meeranhussain, 07-19-2024, 01:49 AM
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115 views
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Is it possible to have a mitochondrial genome of size 30-40kbp in insects? Assembled mitogenome which is 32kb in size
by meeranhussain
Started by meeranhussain, 07-19-2024, 01:43 AM
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208 views
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Qiagen CLC Workbench QIAseqPRO targeted DNA panels - commercial vs own customization of templates
by DarkStar
Started by DarkStar, 07-01-2024, 08:38 AM
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171 views
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by DarkStar
07-01-2024, 08:38 AM
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Single cell RNAseq beginner tutorials: Seurat object and SingleCellExperiment object explained
by crazyhottommy
Started by crazyhottommy, 06-15-2024, 08:34 PM
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236 views
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 02:55 AM
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6 views
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by SEQadmin2
Today, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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