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Sample Prep / Library Generation
Techniques and protocol discussions on sample preparation, library generation, methods and ideas
Topics: 2,201
Posts: 9,924
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2,201 | 9,924 |
by zsasbo
09-19-2026, 11:37 AM
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Single Cell Sequencing
Techniques, discussions, and applications of single cell sequencing.
Topics: 8
Posts: 15
Last Post:
Reference mapping for scRNA seq data?
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8 | 15 |
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Genomic Resequencing
Variant discovery in previously sequenced genomes/regions
Topics: 280
Posts: 994
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280 | 994 |
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De novo discovery
Wandering without a reference? Post here
Topics: 340
Posts: 1,699
Last Post:
Hifiasm and sex chromosomes from XY specimen
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340 | 1,699 |
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Metagenomics
Ever wonder what's growing in that hot spring or glacier?
Topics: 268
Posts: 847
Last Post:
Impact of biomass on shotgun sequencing
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268 | 847 |
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Epigenetics
Any non-primary sequence heritable modification of genetic material. ChIP-SEQ, DNA methylation (Bisulfite-SEQ), chromatin modifications (methylation, acetylation, etc), non coding RNA.
Topics: 357
Posts: 1,578
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357 | 1,578 | |
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RNA Sequencing
Application of sequencing to RNA analysis (RNA-Seq, whole transcriptome, SAGE, expression analysis, novel organism mining, splice variants)
Topics: 2,865
Posts: 11,429
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2,865 | 11,429 |
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Clinical Sequencing
Discuss issues unique to clinical sequencing.
Topics: 38
Posts: 104
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38 | 104 |
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Next-generation sequencing (NGS) is changing how clinical and public health laboratories detect pathogens, track antimicrobial resistance,...10-01-2026, 05:37 AM -
Much of the genetic basis of Alzheimer's disease and related dementias (AD/ADRD) is still unexplained, and some of the answers may sit...10-01-2026, 05:06 AM
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Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM -
Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing... -
The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM