.rod files with annotation for snps - anyone know what these look like?
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> head dbsnp_130_hg18.rod
585 chr1 259 260 rs72477211 0 + C C A/G genomic single unknown 0 0 unknown exact 3
585 chr1 491 492 rs55998931 0 + C C C/T genomic single unknown 0 0 unknown exact 1
585 chr1 518 519 rs62636508 0 + G G C/G genomic single unknown 0 0 unknown exact 1
585 chr1 582 583 rs58108140 0 + G G A/G genomic single unknown 0 0 unknown exact 1
585 chr1 800 801 rs28853987 0 + G G A/G genomic single unknown 0 0 unknown exact 1
585 chr1 876 877 rs28484712 0 + G G A/G genomic single unknown 0 0 unknown exact 1
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by seqadmin
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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04-22-2024, 07:01 AM -
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by seqadmin
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
Channel: Articles
04-04-2024, 04:25 PM -
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