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  • Genome references database with full taxonomy

    Dear experts,

    Is there a database with fully sequenced reference genomes with taxonomy? Better if in one/many fasta-files with taxonomy in headers like
    >Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacteriales;Enterobacteriaceae;Escherichia-Shigella;Escherichia coli str. K-12 substr. DH10B

    There is 16S/18S rRNA database like arb-silva.de for that, but I couldn't find full genome database.

    If such a database does not exists, what is the simplest way to mine this data from other databases (assuming good programming skills)?

    Thank you!

  • #2
    Here's the ftp link for the NCBI taxonomy database:

    ftp://ftp.ncbi.nih.gov/pub/taxonomy/

    I'm not quite sure what you want to use this for. Using FASTA files with full taxa in the headers seems incredibly inefficient.

    If you have NCBI GI numbers for sequences, you can find out the taxon for that sequence:

    ftp://ftp.ncbi.nih.gov/pub/taxonomy/gi_taxid.readme

    And then use the nodes.dmp file from the taxdump database to traverse the complete taxonomy:

    ftp://ftp.ncbi.nih.gov/pub/taxonomy/taxdump_readme.txt

    I guess you could also use the gi_taxid to do a reverse lookup, retrieving all the NCBI sequence GIs with a particular taxid.

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