Hi,
I am trying to assemble a genome from using SOLiD and Illumina paired end data. I have about 30x coverage from Illumina and a similar level from SOLiD. What would be a good assembly program for this? One point I was wondering was that color space assemblers like velvet do not take base space output, so would be okay to convert base space to colorspace? Color space to base space is not recommended as any errors will propagate throughout the read but the other way round should be fine.
I am trying to assemble a genome from using SOLiD and Illumina paired end data. I have about 30x coverage from Illumina and a similar level from SOLiD. What would be a good assembly program for this? One point I was wondering was that color space assemblers like velvet do not take base space output, so would be okay to convert base space to colorspace? Color space to base space is not recommended as any errors will propagate throughout the read but the other way round should be fine.
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