Hi All,
I have 2 set of sequences (belong to two types of samples in one species). I want to enriched motifs in the first set of sequences (using other set as background) and vice versa.
My question is: do I need to adjust for GC content (because there is significant difference in GC content between the two set of sequences)?
I have 2 set of sequences (belong to two types of samples in one species). I want to enriched motifs in the first set of sequences (using other set as background) and vice versa.
My question is: do I need to adjust for GC content (because there is significant difference in GC content between the two set of sequences)?