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-   -   Using scRNA-seq to help with snRNA-seq clustering (http://seqanswers.com/forums/showthread.php?t=95583)

Matt.Kanke 08-11-2020 04:38 PM

Using scRNA-seq to help with snRNA-seq clustering
 
Hi,

I am working with a single nucleotide RNA-seq (snRNAseq) dataset. These are often hard to cluster compared to single cell RNA-seq (scRNAseq). I was wondering if you could combine a snRNAseq and scRNAseq using Seurat's integration method, and after assigning clusters, filter out the scRNAseq cells leaving you with (hopefully) better clustered snRNAseq data to continue the analyses.

Thanks,
Matt


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