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  • Error while running ContEst

    I am trying to run ContEst(http://www.broadinstitute.org/cancer/cga/contest)

    Below is the command and options I used:

    java -Xmx1200m -jar ContEst.jar \
    -T Contamination \
    -I test.bam \
    -R hg19_GATK_Ref.fa \
    -L target_bed_file.bed \
    -Bop,vcf hg19_population_stratified_af_hapmap_3.3.with.chr.vcf \
    -B:genotypes,vcf test.vcf \
    -BTI genotypes \
    -o test.vcf.contest.out.txt

    Here is the error report:

    INFO 17:18:47,638 TraversalEngine - chr15:65621857 1.48e+06 5.2 m 3.5 m 72.4% 7.2 m 119.5 s
    ##### ERROR ------------------------------------------------------------------------------------------
    ##### ERROR stack trace
    java.lang.ArrayIndexOutOfBoundsException: 0
    at org.broadinstitute.cga.tools.gatk.walkers.cancer.contamination.ContaminationWalker.map(Unknown Source)
    at org.broadinstitute.cga.tools.gatk.walkers.cancer.contamination.ContaminationWalker.map(Unknown Source)
    at org.broadinstitute.sting.gatk.traversals.TraverseLoci.traverse(TraverseLoci.java:78)
    at org.broadinstitute.sting.gatk.traversals.TraverseLoci.traverse(TraverseLoci.java:19)
    at org.broadinstitute.sting.gatk.executive.LinearMicroScheduler.execute(LinearMicroScheduler.java:62)
    at org.broadinstitute.sting.gatk.GenomeAnalysisEngine.execute(GenomeAnalysisEngine.java:234)
    at org.broadinstitute.sting.gatk.CommandLineExecutable.execute(CommandLineExecutable.java:113)
    at org.broadinstitute.sting.commandline.CommandLineProgram.start(CommandLineProgram.java:221)
    at org.broadinstitute.sting.gatk.CommandLineGATK.main(CommandLineGATK.java:87)
    ##### ERROR ------------------------------------------------------------------------------------------

    It seems to be some issue with chr15 because I tried it with 3 different bams files and the reference used to generate those bams is also same(same as the one I used with ContEst).

    I am unable to find any such issue reported by anyone else.

    Anybody else having this issue or knows a way around ??
    Last edited by ersgupta; 12-19-2012, 07:30 AM.

  • #2
    Even I had the same error while running ContEst exactly at chr14-15.
    Try it out with smaller bam files it works!

    Anybody solved this error?

    Comment

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