How to show directly the percentage of SNP calling in the final.snp file generated from MAQ, that is, how many percent of ATGC in this final SNP report. Fox example, if A (reference) was changed to G (consensus), what is percentage of this G? At the position, maybe 80% of G, 18% of C, 1% of A, and 1% of T. Is there any column we can add in the final report to show these percentage number? Instead of running the MAQ view function that might create a couple hundred GB data, too big.
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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