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-   -   Chinese reincarnation of Helicos! (http://seqanswers.com/forums/showthread.php?t=64014)

genseq 11-04-2015 10:46 PM

Chinese reincarnation of Helicos!
 
October 27, 2015 Shenzhen, China Direct Genomics today announced the GenoCare, the world's first single molecule genome sequencer that is engineered exclusively for the clinic. The GenoCare improves the cost, speed, and quality of clinical genome sequencing by directly reading a patient's original DNA or RNA molecules.

http://www.pacgeno.com/en/main.html
http://cen.acs.org/articles/93/i43/C...eneration.html
http://www.bio-itworld.com/2015/10/2...echnology.html
http://www.bio-itworld.com/uploadedI...t/GenoCare.jpg

ymc 11-05-2015 08:07 PM

spec? pricing? base accuracy?

DebbyPan 12-14-2015 04:13 AM

I have experience with Helicos sequencer.

The Shenzhen company claimed that their sequencing cost will be a half of Illumina, this is amazing, but probably true because it is made in China.

Do not expect the same throughput as Illumina, because it is based on Helicos technology.

Its substitution error is higher than Illumina, similar to Ion sequencer. They have to sequence up to 2000 times to get the same accuracy as Illumina.

This sequencer will find it position in niche market, such as NIPT, PGS and other clinical application, with its advantage requiring no sample prepare. But you will be disappointed for whole genome sequencing, it is definitely not a good choice for research purpose. I bet they will not sell to university and research institute, no one is going to use it for research, unless the Shenzhen company can publish dozens of high profile journal article to prove it.

Anyway, I believe Shenzhen will be the superpower of genome sequencing, both sequencing service and sequencing machine in the future.

ymc 12-22-2015 11:33 PM

But BGI is also in the NIPT space and they will definitely use their own sequencer. Berry Genomics is also another NIPT competitor using Illumina technology. Not sure how this Helicos reincarnation find a niche to survive in this highly competitive market.

Your last paragraph can be correct but the future most likey will have nothing to do with this Helicos reincarnation if all they can do is aneuploidy.


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