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-   -   Paired-sample (tumor/normal) somatic mutation detection software (http://seqanswers.com/forums/showthread.php?t=10738)

alexischr 04-13-2011 12:19 PM

Paired-sample (tumor/normal) somatic mutation detection software
 
Hi everyone,

I was wondering if anyone here that is working on cancer genomics would have experience with software for detecting tumor mutations using paired normal and tumor genomes (or exomes)? There are a few things out that I'm aware of (VarScan has added somatic support, the '-somatic' option in GATK's IndelGenotyper), but I'm not finding much more than that.

Thank you!

Alexis

RDW 04-14-2011 05:56 AM

You might try this:

http://genome.wustl.edu/software/somaticsniper

See also:

http://www.ncbi.nlm.nih.gov/pubmed/20843826


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