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f85978 03-30-2009 12:21 AM

Illumina or Solid3
Hello, my name is Dorota. I come from Poland, but currently I am working in the Deaprtment of Genetics at King Faisla Hospital and Research Center in Riyadh. I supervise Sequencing Core Facility which is equipped with two Megabeses, two ABI 3130xl and one 3730xl. We generate up to 1500 sequencing reads per day. Our main research interest is a screening of candidate genes related to many different genetic disorders. Now we are going to get one of available NGS platforms. We are taking Illumina and Solid 3into consideration. I would be very grateful for any advices, which one will be better.

joa_ds 03-30-2009 05:52 AM

if you have access to a good analysis team, take the solid. But if you have to use existing products, i'd say, go for the illumina...

The solid produces a huge amount of data which is useless if there is noone that can write scripts and analyse it, especially with the color space. The illumina on the other hand is available with a very 'easy' pipeline, it still takes a linux guy to install and validate it, but at least you can start analysing faster than a solid run.

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