Hi everyone,
I have a rather silly question but I'm hoping someone will clear something up in my head.
Why do people study gene mutations in cancer patients (for example) rather than studying their RNA expression levels, since a mutation doesn't necessarily mean a cell will have a varied mRNA output and therefore a phenotypic change?
There must be some advantages to assessing variants at the DNA level rather than at the RNA level, right?
Thanks!
I have a rather silly question but I'm hoping someone will clear something up in my head.
Why do people study gene mutations in cancer patients (for example) rather than studying their RNA expression levels, since a mutation doesn't necessarily mean a cell will have a varied mRNA output and therefore a phenotypic change?
There must be some advantages to assessing variants at the DNA level rather than at the RNA level, right?
Thanks!
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