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Newsbot! 05-06-2008 02:02 PM

In Sequence: Yale Team Uses an Illumina GA to Sequence Yeast Transcriptome; Finds Gre
 
Syndicated from In Sequence RSS Feed

Sequencing fragmented cDNAs on Illumina’s Genome Analyzer and mapping the reads to the yeast genome, the scientists identified untranslated regions, introns, alternative initiation codons, upstream open reading frames, unexpected 3’ ends, and overlapping genes. The results, which appeared online in Science last week, indicate that “the yeast transcriptome is more complex than previously appreciated,” the researchers write in their study, and pave the way for similar analyses of the human genome.

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