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Forum: Oxford Nanopore 06-16-2015, 10:13 PM
Replies: 10
Views: 3,356
Posted By BBoy
videos of all the talks are up on the ONT website

videos of all the talks are up on the ONT website
Forum: Oxford Nanopore 06-16-2015, 05:18 PM
Replies: 0
Views: 1,321
Posted By BBoy
Compute requirements?

Does anyone have insight into how the higher data rates of the Mk2 devices will impact compute requirements (or even the compute requirements of Mk1)? One of the few papers that deals with this...
Forum: Oxford Nanopore 10-23-2014, 11:58 PM
Replies: 5
Views: 4,755
Posted By BBoy
It took a complete crash of expectations and...

It took a complete crash of expectations and disillusionment, with VCs bailing out, to give PacBio the breathing room they needed. Someone prominent in the community wrote as recently as 2012:

...
Forum: Oxford Nanopore 10-23-2014, 10:00 PM
Replies: 47
Views: 15,226
Posted By BBoy
Reminds me of this. I think at the time it was...

Reminds me of this. I think at the time it was targeted at PacBio, but the author seems to have changed their mind since then.
...
Forum: Oxford Nanopore 10-23-2014, 09:28 PM
Replies: 5
Views: 4,755
Posted By BBoy
You gotta straighten out your metaphors on...

You gotta straighten out your metaphors on multiple points:

This was IBM that the sledge hammer was thrown at. In 1984 Microsoft was not anywhere close to being a monopoly. For crying out loud,...
Forum: The Pipeline 06-03-2014, 07:04 PM
Replies: 19
Views: 18,984
Posted By BBoy
Their hardware, as much as can be judged from...

Their hardware, as much as can be judged from their patents and public presentations is elegant. Murky biochem IP is indeed the right way to characterize things. There are multiple startups,...
Forum: The Pipeline 06-02-2014, 06:47 PM
Replies: 19
Views: 18,984
Posted By BBoy
Brilliant move or sign of desperation on the part...

Brilliant move or sign of desperation on the part of Roche? After sending $60M+ down the drain with IBM they are now back to the big dance, now with (apparently) murky IP situation. ONT has...
Forum: The Pipeline 02-24-2014, 10:10 PM
Replies: 3
Views: 8,008
Posted By BBoy
Funny. If this could be made to work it would be...

Funny. If this could be made to work it would be a hot seller with teens. Someone from Qualcomm actually told me that if they can figure out how to do a good smell sensor it would sell like hotcakes...
Forum: The Pipeline 02-23-2014, 01:03 AM
Replies: 3
Views: 8,008
Posted By BBoy
ONT MAP - what do you plan to do with it?

The silence on SeqAnswers post the Jaffe talk at AGBT has been deafening, perhaps on account of the wide coverage on Twitter (what has the world come to - assessing scientific results 140 characters...
Forum: Illumina/Solexa 01-17-2014, 05:48 PM
Replies: 100
Views: 34,317
Posted By BBoy
Illumina controls the clustering adapters and...

Illumina controls the clustering adapters and sequencing primers. It should be trivial to ensure no Gs at the end of the cluster.
Forum: The Pipeline 01-16-2014, 11:52 PM
Replies: 80
Views: 197,248
Posted By BBoy
Some of the VCs may not fully comprehend the full...

Some of the VCs may not fully comprehend the full barriers to entry over and above the sequencing itself (sample prep, informatics pipelines, understood error profiles, etc) but they are no dummies. ...
Forum: The Pipeline 01-16-2014, 11:05 PM
Replies: 80
Views: 197,248
Posted By BBoy
There was a per-Gb cost estimate for the minion...

There was a per-Gb cost estimate for the minion that somebody posted, I just can't find it right now. It was ~10x that of a Hiseq and ~2-3x that of Pacbio, sample prep and reagents not included. ...
Forum: Illumina/Solexa 01-14-2014, 09:07 PM
Replies: 100
Views: 34,317
Posted By BBoy
See flowcell pics on Twitter @nextgenseek Fat...

See flowcell pics on Twitter @nextgenseek
Fat lanes = different optics
Probably not a typo
Forum: Illumina/Solexa 12-04-2013, 08:56 PM
Replies: 18
Views: 6,772
Posted By BBoy
So how many of you bought video players or Rokus...

So how many of you bought video players or Rokus in 2012 and tried to hook them up to 3+ year old TV without HDMI ports? Betcha you did not think you were screwed by the TV maker and we're...
Forum: The Pipeline 10-21-2013, 10:27 PM
Replies: 80
Views: 197,248
Posted By BBoy
Hopefully more than mockups with plexiglass...

Hopefully more than mockups with plexiglass cutouts like last time around? Unless they show something this will start turning into the mother of all vaporware. Given that there are no leaks (and...
Forum: The Pipeline 10-18-2013, 11:50 PM
Replies: 80
Views: 197,248
Posted By BBoy
Maybe they were shown the foils from AGBT 2011 :-)

Maybe they were shown the foils from AGBT 2011 :-)
Forum: The Pipeline 09-12-2013, 09:49 PM
Replies: 2
Views: 6,196
Posted By BBoy
And this year's installment ...

And this year's installment
http://www.nih.gov/news/health/sep2013/nhgri-06a.htm

Any news from ONT? They have been awfully quiet for nearly 2 years now.
Forum: The Pipeline 09-12-2013, 09:45 PM
Replies: 5
Views: 5,335
Posted By BBoy
And more importantly, how is this better than...

And more importantly, how is this better than established array technology. FET sensing of hybridization has been published time and again over the past 10 years.
Forum: The Pipeline 03-04-2013, 09:39 PM
Replies: 80
Views: 197,248
Posted By BBoy
Apparently we have all been asleep at the wheel. ...

Apparently we have all been asleep at the wheel. The minion has been out for decades, the first model has even made it to a museum:...
Forum: Ion Torrent 02-23-2013, 08:21 AM
Replies: 70
Views: 17,925
Posted By BBoy
Not completely, they seem to be about six months...

Not completely, they seem to be about six months off if you believe the latest statements from Rothberg at AGBT...
Forum: The Pipeline 02-15-2013, 12:30 AM
Replies: 80
Views: 197,248
Posted By BBoy
Well said...

Well said...
Forum: The Pipeline 02-15-2013, 12:03 AM
Replies: 9
Views: 13,188
Posted By BBoy
http://www.nanoporetech.com/technology/publication...

http://www.nanoporetech.com/technology/publications

There is NOTHING there newer than 2010, which is ancient in that field, and all technology papers are generic reviews circa 2007-2008. Exactly...
Forum: Ion Torrent 02-14-2013, 11:53 PM
Replies: 70
Views: 17,925
Posted By BBoy
EVERY supplier has an incentive to lie. Not as...

EVERY supplier has an incentive to lie. Not as "material lie" a la certain UK based company of yesteryear, but certainly exaggeration and puffing up. So far LT has shown a steady improvement, but...
Forum: The Pipeline 08-16-2012, 01:06 AM
Replies: 8
Views: 4,737
Posted By BBoy
How prescient :-)

How prescient :-)
Forum: The Pipeline 08-16-2012, 01:02 AM
Replies: 103
Views: 134,964
Posted By BBoy
They really really really ought to re brand the...

They really really really ought to re brand the damn thing. Minion? Really? But I agree that the silence since AGBT has been interesting, as has been the lack of significant hiring activity. Perhaps...
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