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Forum: The Pipeline 11-15-2012, 09:21 AM
Replies: 9
Views: 13,806
Posted By Nanoporous
Also check out the recent publication by the...

Also check out the recent publication by the Gundlach group on addressing the speed issue using a phi29 polymerase.

There are also other approaches being taken by other companies for reducing...
Forum: The Pipeline 11-08-2012, 01:21 PM
Replies: 80
Views: 203,691
Posted By Nanoporous
Thanks for the very nice summary. For the...

Thanks for the very nice summary.

For the 'gate' protein, I think they are using some sort of a motor protein to slow down the motion of the DNA in a stepwise manner. As per Clive Brown's talk at...
Forum: The Pipeline 11-08-2012, 08:28 AM
Replies: 80
Views: 203,691
Posted By Nanoporous
http://blogs.nature.com/news/2012/11/sequencing-co...

http://blogs.nature.com/news/2012/11/sequencing-companies-show-off-for-genetics-meeting.html
Forum: The Pipeline 11-07-2012, 11:38 AM
Replies: 80
Views: 203,691
Posted By Nanoporous
Thanks for the info. Getting the same vibe from...

Thanks for the info. Getting the same vibe from following other Twitter accounts - no data yet.

On the other hand, they are doing some cheeky marketing:
...
Forum: The Pipeline 02-22-2012, 08:53 AM
Replies: 103
Views: 135,641
Posted By Nanoporous
Rothberg's comments are perhaps a bit extreme,...

Rothberg's comments are perhaps a bit extreme, and always comes with the 'he's a competitor' tag, but after the initial euphoria, lot of people at AGBT associated with both genome sequencing...
Forum: The Pipeline 02-21-2012, 09:11 AM
Replies: 103
Views: 135,641
Posted By Nanoporous
He showed very little data. There was certainly...

He showed very little data. There was certainly no data showing simultaneous currents. He did show some current versus time traces and how they remove the time information to obtain a spatial trace....
Forum: The Pipeline 02-21-2012, 06:21 AM
Replies: 51
Views: 168,385
Posted By Nanoporous
They are certainly not using a polymerase; they...

They are certainly not using a polymerase; they have developed their own 'motor-protein enzyme' by screening 300+ mutations of some natural enzyme (possibly a helicase?).

Their nanopore array is...
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