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Forum: Bioinformatics 08-07-2012, 07:23 AM
Replies: 1
Views: 2,730
Posted By Groningen
filtering strategy in exome sequencing and quality control

To filter exome sequence data and remove false positive I know read depth and Phred score are routinely applied.

But there are following items (related to quality) which I would like to know is...
Forum: General 08-07-2012, 06:43 AM
Replies: 2
Views: 2,597
Posted By Groningen
hg19 or hg18 are different built.depend on what...

hg19 or hg18 are different built.depend on what method, what kind of kit and what bioinformatics method you have applied to have a sequence data from one person, you will have his/her sequence data...
Forum: The Pipeline 04-11-2012, 07:15 AM
Replies: 0
Views: 2,858
Posted By Groningen
Question finding compound mutations in Excel file

I am looking for causative mutations for a recessive autosomal disease. I have an excel file consist of exome sequence data of parents and one affected child. The question is there any way/...
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