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Forum: RNA Sequencing 08-12-2014, 03:42 PM
Replies: 24
Views: 11,348
Posted By chaoxing
Pr(K=k)=(k+r-1,r-1)p^r(1-p)^k, you set...

Pr(K=k)=(k+r-1,r-1)p^r(1-p)^k,
you set p=u/sigma^2, r=u^2/(sigma^2-u),

p and r are derived from here.

Thank you.
Forum: RNA Sequencing 08-12-2014, 02:38 PM
Replies: 24
Views: 11,348
Posted By chaoxing
Smile Some questions about DESeq and DESeq2

Hi Simon,

I have three questions about DESeq here(referring to "Differential expression analysis for sequence count data"):

1. You set up three assumptions, what is the basis of equation(3) and...
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