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Forum: Epigenetics 12-24-2017, 09:50 AM
Replies: 0
Views: 3,149
Posted By salamandra
Talking Transcription factors and closed/activated/repressed chromatin

Is it possible for a TF to bind to closed chromatin without opening it? I mean, is it possible for chip-seq peaks of non-pioneer TFs to exist in closed chromatin?

If it is, can we assume that TF...
Forum: General 11-10-2017, 02:26 AM
Replies: 8
Views: 14,027
Posted By salamandra
But does anyone know what causes GC bias during...

But does anyone know what causes GC bias during PCR? Why is there a tendency for amplyfing more or less GC-rich DNA fragments?
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