Forum: Bioinformatics
09-23-2014, 08:12 PM
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Replies: 3
Views: 7,128
Hi, thank you very much. I realized that...
Hi, thank you very much. I realized that Psi-blast is an option available through blastp. Seems like Psi-blast is more rigorous that blastX.
I am little bit confused about the difference between...
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Forum: Bioinformatics
09-21-2014, 06:05 PM
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Replies: 3
Views: 7,128
tblastn and blastx question
It says that tblastn is more likely to find distantly related sequences than the blast, blasts, and blastp. I wonder why is it? I generally use Blastx.
By definition, tblastn compares query...
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Forum: Bioinformatics
07-27-2014, 05:24 PM
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Replies: 0
Views: 1,393
GC-content normalization
Can anyone please explain the how the normalization is done for GC-content bias?
I read the papers but could not get the grasp of the statistical method used.
"Understanding mechanisms...
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Forum: Bioinformatics
07-25-2014, 08:34 PM
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Replies: 7
Views: 4,884
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Forum: Bioinformatics
07-17-2014, 07:48 AM
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Replies: 7
Views: 4,884
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Forum: Bioinformatics
07-16-2014, 05:44 AM
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Replies: 7
Views: 4,884
Thank you for the quick response and...
Thank you for the quick response and clarification. Would you mind providing some insight into how the calculation is done and what that component factor stands for in the equation.
Thanks!
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Forum: Bioinformatics
07-15-2014, 02:06 PM
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Replies: 7
Views: 4,884
calculate TMM normalization
Hello all,
I would like to calculate TMM normalization for identifying DE genes. I know that edgeR does all the normalization when you run the code but I would like to calculate TMM for one or...
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Forum: Bioinformatics
06-05-2014, 08:57 PM
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Replies: 0
Views: 1,231
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