Forum: Bioinformatics
02-05-2015, 06:48 AM
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Replies: 4
Views: 1,347
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Forum: Bioinformatics
01-02-2015, 07:27 AM
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Replies: 3
Views: 2,425
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Forum: Bioinformatics
12-13-2014, 02:37 PM
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Replies: 7
Views: 1,655
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Forum: Bioinformatics
12-12-2014, 06:28 AM
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Replies: 13
Views: 3,485
The end problem was first mentioned in a 2008...
The end problem was first mentioned in a 2008 paper and then rediscovered multiple times after that. The problem subsequently motivated the development of GATK realignment, SRMA, samtools BAQ and...
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Forum: Bioinformatics
12-09-2014, 06:19 PM
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Replies: 11
Views: 3,578
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Forum: Bioinformatics
12-07-2014, 09:49 AM
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Replies: 11
Views: 13,335
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Forum: Bioinformatics
12-06-2014, 09:00 AM
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Replies: 4
Views: 2,707
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Forum: Bioinformatics
11-25-2014, 06:20 PM
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Replies: 1
Views: 2,075
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Forum: Bioinformatics
10-28-2014, 04:58 AM
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Replies: 7
Views: 1,420
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Forum: RNA Sequencing
10-27-2014, 05:01 AM
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Replies: 6
Views: 3,007
*_random sequences could be unique sequences in...
*_random sequences could be unique sequences in heterochromatin or a large segdup where the flanking cannot be localized or placed. We use these sequences in mapping to reduce mapping artifacts, not...
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Forum: Bioinformatics
10-21-2014, 06:17 PM
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Replies: 11
Views: 13,335
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Forum: General
10-21-2014, 06:14 PM
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Replies: 9
Views: 2,079
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Forum: Bioinformatics
10-21-2014, 05:02 PM
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Replies: 11
Views: 13,335
See...
See https://gist.github.com/lh3/54f535b11a9ee5d3be8e
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Forum: Bioinformatics
10-15-2014, 03:03 PM
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Replies: 3
Views: 1,679
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Forum: Bioinformatics
10-10-2014, 09:25 AM
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Replies: 35
Views: 14,600
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Forum: Bioinformatics
10-09-2014, 01:57 PM
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Replies: 35
Views: 14,600
I see, it is conditioned. Then I understand why...
I see, it is conditioned. Then I understand why you say Picard's model is a special case of ZTNB.
Another question. Why did you say in bw's plot preseq cannot be compared to picard? Isn't preseq's...
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Forum: Bioinformatics
10-09-2014, 11:03 AM
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Replies: 35
Views: 14,600
Someone was asking me about library size...
Someone was asking me about library size estimate. Google search directed me to this interesting thread. I have a question about your ZTNB model.
I briefly skimmed through the supplementary note....
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Forum: Bioinformatics
10-03-2014, 07:00 AM
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Replies: 10
Views: 3,465
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Forum: Bioinformatics
10-02-2014, 07:27 PM
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Replies: 10
Views: 3,465
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Forum: Bioinformatics
09-25-2014, 06:04 PM
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Replies: 8
Views: 2,216
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Forum: Bioinformatics
09-25-2014, 12:27 PM
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Replies: 8
Views: 2,216
PacBio assembly of CHM1 is here:
...
PacBio assembly of CHM1 is here:
http://www.cbcb.umd.edu/software/PBcR/MHAP/
It is different from the version I was looking at, but I believe it should be equally good. The NA12878 PacBio...
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Forum: Bioinformatics
09-20-2014, 08:40 PM
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Replies: 8
Views: 2,216
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Forum: Illumina/Solexa
09-11-2014, 06:23 PM
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Replies: 1
Views: 1,271
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Forum: Bioinformatics
09-11-2014, 06:19 PM
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Replies: 9
Views: 6,801
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Forum: Illumina/Solexa
09-05-2014, 07:01 AM
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Replies: 25
Views: 5,051
As to cost, Illumina is advertising $1000 human...
As to cost, Illumina is advertising $1000 human genomes at 30X coverage. The first human genome sequenced by PacBio at 54X coverage costs around $60k-80k. The price difference is still considerable....
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