So what is the update with this project https://github.com/nh13/samtools . Is it still faster than multi-threaded version of samtools ? Is this going to be a good substitute for Goby and Cram ?
-
-
Has there been any success on mpileup speedup ? Is the parallelization by pthreads or MPI ?Comment
-
Is the bcftools that come with samtools also multithreaded ?Comment
-
There was no desire from the folks maintaining samtools to take over the development and add it. Sorry for the delayed response.Originally posted by narain View PostComment
-
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
Comment