help! what is a paired-end read?

hitdavid

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Join Date: Jan 2010

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help! what is a paired-end read?

01-14-2010, 08:19 AM

I am a newer in this area.
Could anybody tell me what is a paired-end read?

someone told me that a paired-end read is a read with the two 3' end sequences were sequenced.

for example: a fragment of DNA strands like this

3' 5'
ATTTGCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXATTCGG
5' 3'

and this is used in an assembly process when sequencing.

I am confused by his answer.
Is his answer right? if not, please give me a right answer!
Thank you N*very much!
Tags: paired-end
spenthil

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Join Date: Sep 2009

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01-14-2010, 12:42 PM

what is a paired-end read? - SEQanswers

http://seqanswers.com/forums/showthread.php?t=503

Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc

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Senthil Palanisami
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