Comparison of NGS analyser tech info

[gavin.oliver]

Hi all,

I'm sure this question has been asked before so maybe I'll just be pointed to an old thread, but:

Basically I'm looking for an up-to-date comparison of the major NGS analysers' main technical info - perhaps in table format?

Thanks in advance,

Gavin

[gavin.oliver]

Does noone have any ideas on this?

It would be aprticularly useful to get an idea of the cost per run of the major contenders (454, Solid, Solexa).

Thanks in advance

[gavin.oliver]

I found this comprehensive comparison:

http://genomics.ucr.edu/about/reports/SequencerComparison1207_Table.pdf

Can someone advise whether any of the info is very outdated? I think the document is from March 2008.

Thanks

[ffinkernagel]

there's http://www.clcngs.com/2008/12/ngs-platforms-overview/ which has some about everything but the price per base.

[gavin.oliver]

Really useful, thanks

I'm a newbie so forgive me for asking - Do the Solid 1 and 2 and Solexa GA and GA II represent old (outdated) models?

[ffinkernagel]

Not being immensely familiar with them myself, I know the GAIIx is an upgrade to the GAII machine, and I presume the GA is an older machine.

Please note that the list always contains the 'largest run' - ie. you can run a GAIIx with only 36 bp which makes a single run considerably faster (but in the end I guess is about the same/a little less throughput, but lower latency)

[VanessaS]

Really useful, thanks

I'm a newbie so forgive me for asking - Do the Solid 1 and 2 and Solexa GA and GA II represent old (outdated) models?

I can only speak about the SOLiD, 1 and 2 are old versions. They have come out with the 3, the 3+, and in a month or two will bring out 4. By the end of the year (we shall see) 4hq. Times are a changin'!

[gavin.oliver]

I'm a bit confused about the accuracies. Some sources suggest Illumina is more accurate than ABI and some suggest the opposite. The specs on their respective websites would seem to suggest that the SOLiD is currently the most accurate when running at full capacity.

[avilella]

Next Generation Sequencing spreadsheet

Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?key=0AvaxS3m5rl-9dHdtUGRtaGlsZWNFNWJleDRXaUhQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.

If you want to embed it to a webpage, you can copy+paste the following link:

<iframe width='500' height='500' frameborder='0' src='http://spreadsheets.google.com/pub?key=twmPdmhilecE5bex4WiHPLw&single=true&gid=0&range=A2%3AR25&output=html&widget=true'></iframe>

[Xi Wang]

Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?key=0AvaxS3m5rl-9dHdtUGRtaGlsZWNFNWJleDRXaUhQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.

Oh my god, I can't access google spreadsheet from China..

[KevinLam]

Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?key=0AvaxS3m5rl-9dHdtUGRtaGlsZWNFNWJleDRXaUhQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.

If you want to embed it to a webpage, you can copy+paste the following link:

<iframe width='500' height='500' frameborder='0' src='http://spreadsheets.google.com/pub?key=twmPdmhilecE5bex4WiHPLw&single=true&gid=0&range=A2%3AR25&output=html&widget=true'></iframe>

Nice work!

[RockChalkJayhawk]

Cost per run of different platforms

I'm trying to get a rough idea of how much it costs every time you turn on one of these instruments. Can you all help approximate? I know it vaires on application, so a range is acceptable.

I know the HiSeq is ~$20K (10K if just one flow cell), but what about
GAIIe:
SOLiD4:
SOLiD PI:

?

[ymc]

Oh my god, I can't access google spreadsheet from China..

That's why BGI set up shop in Hong Kong.

[ymc]

Hi all,

I've generated a spreadsheet with the numbers I've compiled from different blogs and news announcements.

http://spreadsheets.google.com/ccc?key=0AvaxS3m5rl-9dHdtUGRtaGlsZWNFNWJleDRXaUhQTHc&hl=en_GB

If anyone has any corrections or knows any other systems or data points, I've made editing public.

If you want to embed it to a webpage, you can copy+paste the following link:

<iframe width='500' height='500' frameborder='0' src='http://spreadsheets.google.com/pub?key=twmPdmhilecE5bex4WiHPLw&single=true&gid=0&range=A2%3AR25&output=html&widget=true'></iframe>

Is this really correct? I think on Illumina's official page, HiSeq 2000 is max 200Gb/run and GAIIx is max 50Gb/run.

[Xi Wang]

That's why BGI set up shop in Hong Kong.

So does google...