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Old 02-13-2014, 05:25 AM   #11
Location: New York

Join Date: Jun 2010
Posts: 11

Water baths send random sound waves through the tank and generally give inconsistant results. Standard water baths operate at 40kHz which is low intensity and too weak for sample processing. These are really made for cleaning.
Cup horns are made to deliver sonication directly to the area where the sample tubes are located plus cup horns offer adjustable intensity settings. You can dial in the setting needed for your particular sample.

Newer high intensity cup horns are now sold specifically for ChIP and DNA shearing and work very well.
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