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  • WhatsOEver
    Senior Member
    • Apr 2012
    • 215

    Bioinformatics postdoc in single cell cancer research at Fraunhofer, Regensburg

    The Chair of Experimental Medicine and Therapy Research, University of Regensburg, and the Fraunhofer Project Group for Personalized Tumor Therapy are building a new center for single cell genomics. The focus will be on the development of novel diagnostic assays and therapies. For this we have developed a variety of single cell techniques and generated a huge sample and databank of single disseminated tumor and circulating tumor cells, among them the putative founder cells of lethal metastasis.

    What we expect from you
    - You hold a Ph.D. or equivalent experience in Bioinformatics, computational biology or a related field or a PhD in molecular biology with a main focus on Bioinformatics and/or Biostatistics
    - You have demonstrated skills in at least one of the following programming languages: Java, Perl, Python, C++, R
    - You have pertinent experience in Linux and in shell scripting
    - You feel comfortable with dealing with a variety of data types and have a solid understanding of statistics for biology
    - You are a team player with good oral and written communication skills
    - You have general knowledge of NGS and/or microarray data analysis
    This would be an asset
    - Demonstrated skills in RNA-seq, WES, WGS and/or array-CGH
    - Experience with relational databases (Postgres, MySQL)
    - Experience with working on deadlines and being involved simultaneously in multiple projects

    What you can expect from us
    You will analyze complex data sets in the area of single cell diagnostics to address different biomedical issues. In close contact with biomedical groups you will develop and implement new analytical processes to analyze high-throughput data. In particular, the major focus of the work will be on the adaptation of existing software routines in conjunction with biostatistical analysis to build up a data analysis pipeline for array CGH, gene expression microarray data and next generation sequencing applications.

    Appointment, remuneration and social security benefits based on the public-sector collective wage agreement (TVöD).
    The working time consists of 39 hours per week.
    The position is initially limited until 31.12.2016.
    In case of identical qualifications, preference will be given to severely disabled candidates.
    The Fraunhofer-Gesellschaft is committed to providing equal career opportunities for men and women.

    Fraunhofer is Europe’s largest application-oriented research organization. Our research efforts are geared entirely to people’s needs: health, security, communication, energy and the environment. As a result, the work undertaken by our researchers and developers has a significant impact on people’s lives. We are creative. We shape technology. We design products. We improve methods and techniques. We open up new vistas.

    Interested candidates should apply via our online application system: https://recruiting.fraunhofer.de/Vac.../Description/2
    The closing date for this position is June 20th, 2015

    Informal inquiries should be sent to urs.lahrmann[at]item.fraunhofer.de

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  • GATTACAT
    Reply to Nine Things a Sample Prep Scientist Thinks About Before Sequencing
    by GATTACAT
    Love this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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  • SEQadmin2
    Nine Things a Sample Prep Scientist Thinks About Before Sequencing
    by SEQadmin2


    I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.

    Here are nine questions we think about, in roughly the order they matter, before...
    06-18-2026, 07:11 AM

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