How to detect the pathways or do pathway comparison with the help of BGC's ?
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What exactly is a BGC in this context? -
Biosynthetic gene cluster ... from a previous post by @sushant.Originally posted by dpryan View Post
@sushant: If you know the boundries of the clusters you surely you can get some idea about what that cluster is producing by looking at the genes present. This (and your previous post on a similar topic) are rather vague.Comment
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
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