I am interested in methadologies for comparing the results of multiple ChIP-Seq studies (i.e. multiple transcription factors, TFs and histone modifications). Does anyone know of good resources for doing this?
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I'm not sure what your specific aims are but you can try Catch (http://catch.cmbi.ru.nl/) or ChromaSig (http://bioinformatics-renlab.ucsd.ed...wiki/ChromaSig).
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
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