Are there any new alternatives out there for size selection other than the Pippin prep? I saw some older posts on the LabChip XT but don't know if that is even manufactured at this point. I also saw some on the E-gel; it didn't look like it was useful for libraries. Information on any recent worthy alternatives that should be considered would be appreciated (100 - 750 bp range).
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SageElf
Also, has anyone used the SageElf? It fractionates the entire DNA smear into separate tubes by rotating the electrical field 90 degrees. -
Coastal Genomics has a very high throughput instrument.Comment
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We will also be showcasing a lower-throughput option that can integrate with robotic platforms or be used by a technician as SLAS in Washington DC. Please message me if you would like more details.Comment
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
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