In IGV what does a variant found only in white space denote. I don't think its real but trying to figure it out. For example, in the attached all the C are located in the white space. Thank you 
.
.
-
-
I'm not sure because the fill can be set via preferences to denote various characteristics of the read. But it is attractive to think that it might denote in this case a failure to map the paired read? Attractive because that would suggest that the locus has a paralog elsewhere in the genome with a slightly different sequence.
--
Phillip -
The default meaning for a white read with a grey outline is that the read cannot be uniquely mapped. it can be mapped to more than 1 location.Comment
-
The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM
Comment