I have used CIRI software to identify circRNA. how to calculate circRNA and mRNA expression level without depletion of linear RNA? Is there any tools or workflow avaliable for this?
Thanks a lot!
Thanks a lot!
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happy -
I have just read your post and maybe our tool "CirComPara" suits your needs (if you still need it, I see the post is quite old). It is an automated pipeline that performs linear transcript and gene expression analysis, and circRNA detection, quantification and characterization, also correlating linear and circular expression patterns.
It's availabe from here https://github.com/egaffo/CirComPara and the related paper describing it http://www.mdpi.com/2311-553X/3/1/8.
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The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM
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