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  • jenniferpham
    Junior Member
    • Jun 2018
    • 7

    BioTuring Browser: published single-cell RNA-seq data analysis made easy

    Hi everyone,

    I am glad to let you know about the official release of BioTuring Browser, the platform to resolve major challenges in single-cell RNA-seq data analysis.

    With the proliferation of the single-cell RNA-seq data, we are now facing a major bottleneck in data analysis, because such enormous amounts of data require really hard code to process, and a strong computer to visualize thousands to millions of data points (i.e. thousands to millions of cells).

    With BioTuring Browser, we aim to make single-cell RNA-seq data analysis extremely easy and compact for every biologist. The package can run well on a standard laptop, show up in an interactive interface that is simple to use, and provide all the state-of-the-art analyses for scRNA-seq data.

    Here's to list a few features in BBrowser:
    • Interactive 3D/2D visualizations of up to 1 million cells on a standard laptop
    • Real-time cell type prediction
    • Batch effect removal (https://www.youtube.com/watch?v=0N7vouZqEoo&t=2s)
    • Differential expression analysis
    • Cell population comparison
    • The ability to select and label cell clusters for further annotation
    • Sub-clustering
    • View 2 genes' expression at the same time
    • View box plots/ violin plots of the expression levels across all the groups


    Future enhancements will include pseudotime trajectory reconstruction, the ability to search for similar single cell populations, and to combine them into the current study.

    Also, BBrowser provides a rich library of scRNA-seq datasets from latest published studies, all processed and ready for visualization and reanalysis. The purpose is to remove any barriers to access valuable published data, and make science completely transparent.



    As a start, BioTuring Browser features nearly 400 publications, including almost all the recent single-cell RNA sequencing datasets and nearly 16,500 samples from bulk RNA sequencing.

    BBrowser is available for Windows, Mac, and Linux at: https://bioturing.com

    Feel free to raise your questions. If you are interested, please subscribe to be the first to hear about BioTuring Browser official release.
    Last edited by jenniferpham; 12-12-2018, 02:51 AM.
    Jennifer Pham
    BioTuring Team
    www.bioturing.com
    BioVinci: modern data visualizations and analysis for life sciences (https://vinci.bioturing.com)
    BioTuring Browser: making access to published single-cell sequencing data as easy as surfing the web (https://bioturing.com/product/bbrowser)
    Our blog: https://blog.bioturing.com
  • jackson48
    Junior Member
    • Jun 2018
    • 2

    #2
    nice, when is it available?

    Comment

    • jenniferpham
      Junior Member
      • Jun 2018
      • 7

      #3
      Originally posted by jackson48 View Post
      nice, when is it available?
      Hi Jackson, the beta version is now available at https://bioturing.com
      Jennifer Pham
      BioTuring Team
      www.bioturing.com
      BioVinci: modern data visualizations and analysis for life sciences (https://vinci.bioturing.com)
      BioTuring Browser: making access to published single-cell sequencing data as easy as surfing the web (https://bioturing.com/product/bbrowser)
      Our blog: https://blog.bioturing.com

      Comment

      • jenniferpham
        Junior Member
        • Jun 2018
        • 7

        #4
        BioTuring Browser was featured on Genomeweb: https://www.genomeweb.com/informatic...a#.W7c2iRP7SnQ
        Jennifer Pham
        BioTuring Team
        www.bioturing.com
        BioVinci: modern data visualizations and analysis for life sciences (https://vinci.bioturing.com)
        BioTuring Browser: making access to published single-cell sequencing data as easy as surfing the web (https://bioturing.com/product/bbrowser)
        Our blog: https://blog.bioturing.com

        Comment

        • jackson48
          Junior Member
          • Jun 2018
          • 2

          #5
          Originally posted by jenniferpham View Post
          Hi Jackson, the beta version is now available at https://bioturing.com
          Hello Jennifer, thanks for your reply. I have a couple of questions that might need your help:
          - Is it for published data only?
          - Do you charge on it?
          - What are the system requirements for this tool?
          - Could you share when the pseudotime is ready for use?

          Thanks,
          Jack.

          Comment

          • jenniferpham
            Junior Member
            • Jun 2018
            • 7

            #6
            Hi Jackson, you can analyze both the published data (free) and private data (charged) in BBrowser. The package can run well on 8GB RAM Mac, Windows, and Linux machines.
            We are going through final testing for the pseudotime and will soon bring it out. You can go to bioturing.com/product/bbrowser to subscribe to get updated about it.
            Jennifer Pham
            BioTuring Team
            www.bioturing.com
            BioVinci: modern data visualizations and analysis for life sciences (https://vinci.bioturing.com)
            BioTuring Browser: making access to published single-cell sequencing data as easy as surfing the web (https://bioturing.com/product/bbrowser)
            Our blog: https://blog.bioturing.com

            Comment

            • jenniferpham
              Junior Member
              • Jun 2018
              • 7

              #7
              Batch effect removal and differential expression analysis have been added to BBrowser in the next release: https://www.youtube.com/watch?v=0N7vouZqEoo&t=2s
              Jennifer Pham
              BioTuring Team
              www.bioturing.com
              BioVinci: modern data visualizations and analysis for life sciences (https://vinci.bioturing.com)
              BioTuring Browser: making access to published single-cell sequencing data as easy as surfing the web (https://bioturing.com/product/bbrowser)
              Our blog: https://blog.bioturing.com

              Comment

              • jenniferpham
                Junior Member
                • Jun 2018
                • 7

                #8
                Exploring the single-cell atlas of the maternal-fetal interface https://www.youtube.com/watch?v=YgkzT2fsvk8
                Jennifer Pham
                BioTuring Team
                www.bioturing.com
                BioVinci: modern data visualizations and analysis for life sciences (https://vinci.bioturing.com)
                BioTuring Browser: making access to published single-cell sequencing data as easy as surfing the web (https://bioturing.com/product/bbrowser)
                Our blog: https://blog.bioturing.com

                Comment

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