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Hello All, the covaris S2 maintenance schedule says I should use 10% bleach for a monthly rinse, can I use a HazTab soultion or household bleach? or should I make up a NaOCL solution?
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Covaris bleaching
A simple apx 10% solution of a household bleach like Clorox will be fine. No need to mix up NaOCl from scratch, but if you do, remember that Clorox is already a 6% (roughly) solution of NaOCl. You are looking for a relatively mild solution.
After running the bleach solution to retard algae, rinse the system with clean water a couple of times, and keep in mind that once diluted, bleach has a shelf life, so it's probably best to mix new each time.
I hope this answers your question.Last edited by CovarisQual; 10-13-2011, 01:25 PM.
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I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...06-18-2026, 07:11 AM -
Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM
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