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  • doc.ramses
    Member
    • Jan 2011
    • 26

    #1

    GATK update changes UnifiedGenotyper output

    Hey,

    recently I upgraded to the latest version (GenomeAnalysisTK-1.2-1-g33967a4) and I noticed that when I run the UnifiedGenotyper with standard settings, I don't get the "SB" value, that I need for hard-filtering. When I ran the UG of the previous version with standard settings, I got it.
    How can I set for this parameter in the new version ?

    Cheers!
  • Bukowski
    Senior Member
    • Jan 2010
    • 388

    #2
    GATK 1.2 release notes: http://www.broadinstitute.org/gsa/wi...TK_release_1.2

    From release notes:

    "SB annotation is no longer calculated by default; use --computeSLOD to turn it on. Users should check out the FS annotation for a Fisher's exact test of strand bias."

    Comment

    • doc.ramses
      Member
      • Jan 2011
      • 26

      #3
      Thank you for pointing this out!

      Comment

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