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Can anyone point me to where I can find public information on the design of the integrated flow cell that Ion Torrent uses in their chips? I don't need great details - basic channel layout and rough dimensions, etc, would be sufficient. From the videos and pics out there it just looks like a molded shell with one inlet and one outlet port and no particular structure in between. Is that all?
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Last edited by BBoy; 03-13-2012, 06:44 PM. -
this thread links to some interesting documents. You can also read their nature paper which goes in to specific details.
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Fabbing a chip washing station??
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Heck no, just curious. I doubt that once set in place by Van der Waals forces there is any type of external agitation that could effectively dislodge a significant number of beads. But if someone comes up with a method it would put a serious dent into Life's consumables revenue stream.Comment
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Has anyone run the Paired-End method yet? I heard there is prep off the instrument to do the enzymatic steps for the second read. If you looked at the beads/reads present in read 1 and then present in read 2 it could give an indication on how well the beads stay in the wells.Comment
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I had you in mind when I asked that question.Originally posted by genseq
This is for another thread, but I would love to hear more about what you're doing, given all the spy documents you post.
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Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM -
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...05-22-2026, 06:42 AM
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