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Is there any software available at the moment for looking at data from illumina Omni arrays?
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crlmm supposedly can also call genotypes for Omni arrays. However, I tried their 1.6.2 and found genotyping errors in the chrX SNPs. Not sure if it is fixed in their latest version though. -
Illumina Omni CNV analysis
Hi,
I have problem in analyzing CNV for one sample. In this sample LRR profile around(0.0) remains FLAT, though not BAF profile (0.6 & 0.4) and as per ASCAT (software I am using) there is no copy number change.
Has any of you come across a similar issue?
Was wondering if it possible to analyze data with low cellularity and is more a technical issue of the software I am using.
Any pointers would be very helpful.
Best
ShrutiComment
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Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM -
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...05-22-2026, 06:42 AM
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