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I have few genes for a grass species. now I want to compare the structure of these genes (like length of gene and protein, no. of exons and introns, size of exons and introns, GC content in these regions, etc) with their homologs from other sequenced genomes. Any suggestions or softwares that can do this analysis in one go? Thank you
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Have a look at FeatureStack. Disclaimer: I am author of this program. -
Is it this paper: http://bioinformatics.oxfordjournals...nt/28/23/3137?Originally posted by Gig77 View Post
This software is for visualizing the comparisons when one has the gene data on hand, correct? OP wants to find and then display this information.Comment
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Mauve (http://gel.ahabs.wisc.edu/mauve/) is worth a try, if your target genomes are not very dissimilar.Originally posted by manojdarolia View Post
You could also use blast/blat searches, identify the homologous regions in new genomes and then use the software in post #2.Comment
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Yes, that is correct. You need to have gene models first.Originally posted by GenoMax View PostComment
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Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM -
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...05-22-2026, 06:42 AM
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