Hi all,
I am a cufflinks user and I am trying to test other popular gene expression analysis tools such as edgeR and DESeq. In most of my projects we only have one Normal and one Tumor sample. Though there has been a lot of discussions, it is still unclear to me if edgeR or DESeq is "better" than cuffdiff when there are no biological replicates.
Any advice will be appreciated.
I am a cufflinks user and I am trying to test other popular gene expression analysis tools such as edgeR and DESeq. In most of my projects we only have one Normal and one Tumor sample. Though there has been a lot of discussions, it is still unclear to me if edgeR or DESeq is "better" than cuffdiff when there are no biological replicates.
Any advice will be appreciated.
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