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Old 03-14-2014, 11:34 AM   #8
replicate
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From the Lahr paper above, the indication is that chimeras are a pitfall of PCR generally, and while the paper uses next-gen polymerases, this is simply because no-one has(had) looked at recombination and Phu etc. before - is there anything suggesting that hi-fidelity polymerases are more prone to chimera-formation/dropping extension runs?
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