Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • oncoNcRNA: Exploring the ncRNAs with Oncogenic Potentials in Human Cancers

    We had released oncoNcRNA, a web portal for explore the ncRNAs (lncRNAs, miRNAs, piRNAs, snoRNAs, tRNAs) with oncogenic potentials in 64 human cancer types (>20000 tumor samples and ~900 cancer cell lines). It is a valuable tool for investigating the function and clinical relevance of ncRNAs in human cancers.

    oncoNcRNA web site: http://rna.sysu.edu.cn/onconcrna/

    1. The portal characterizes the somatic copy number alterations (SCNAs) and expression of over 58,000 long non-coding RNAs (lncRNAs), 34,000 piwi-interacting RNAs (piRNAs), 2700 microRNAs (miRNAs), 600 transfer RNAs (tRNAs) and 400 small nucleolar RNAs (snoRNAs) in 64 human cancer types by integrating the data from The Cancer Genome Atlas (TCGA), Cancer Cell Line Encyclopedia (CCLE), Progenetix, and several independent studies.

    2. We have discovered a large number of ncRNAs which are frequently amplified or deleted within and across tumor types using oncoNcRNA portal.

    3. We built a web-based tool, Correlations, to explore the relationships between gene expression and copy number from ~10,000 tumor samples in 36 cancer types identified by The Cancer Genome Atlas (TCGA) .

    oncoNcRNA paper is available at http://www.mdpi.com/2311-553X/3/1/7

    oncoNcRNA workflow:
    Last edited by yjhua2110; 02-08-2017, 06:17 PM.

Latest Articles

Collapse

  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin


    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...
    Yesterday, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, 04-11-2024, 12:08 PM
0 responses
55 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-10-2024, 10:19 PM
0 responses
51 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-10-2024, 09:21 AM
0 responses
45 views
0 likes
Last Post seqadmin  
Started by seqadmin, 04-04-2024, 09:00 AM
0 responses
55 views
0 likes
Last Post seqadmin  
Working...
X