GenomeWeb reported yesterday that Sigma-Aldrich was going to co-market the Genius sequencer. There was no launch date mentioned.
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NanoString Developing Novel Sequencing Chemistry Based on Optical Barcoding
At the JP Morgan Healthcare Conference, NanoString Technologies CEO Brad Gray said that the firm has been developing a novel single-molecule hybridization-based sequencing chemistry that leverages the company's optical barcoding technology.
Gray declined to provide details on the chemistry, which he dubbed Hyb&Seq, but said that it would be single-molecule, based on hybridization, and would not require amplification, the use of enzymes, or even library prep.
[Link to Genomeweb article]
[Link to NanoString Presentation]
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...-
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