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Old 08-27-2015, 11:59 AM   #4
Location: Cambridge, UK

Join Date: Aug 2012
Posts: 13

And to extend my question, would I be fine to apply a LOESS transformation? It appears to me that in some of my conditions, there are very active targets, which then cause a bias in reads. Thus, a LOESS transformation may be relevant. Here are some plots of my data, MA plots given on the right side of the diagonal.

(Here's the link in case the picture doesn't show: )

Last edited by simon_seq; 08-27-2015 at 12:00 PM. Reason: Link doesn't work.
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