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Old 08-27-2015, 12:11 PM   #5
dpryan
Devon Ryan
 
Location: Freiburg, Germany

Join Date: Jul 2011
Posts: 3,480
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The trick is to not transform the data at all. Leave the data untouched and supply offsets and such to produce the needed normalization. Again, see how the CQN package and DESeq2 interact.
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