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Old 12-13-2011, 03:06 PM   #1
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Location: Palo Alto

Join Date: Apr 2009
Posts: 213
Default Alignment to b37 with decoy sequences

Hi all,

I've heard from 1kG that alignment to b37 with decoy sequences is superior to without decoy sequences. Obviously the decoy is there to improve our results, but I'm just wondering if others here are using it and, if so, how your results have improved (or if they haven't, what the problem is).

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Breakway: A Program to Identify Structural Variations in Genomic Data [Website] [Forum Post]
Projects: U87MG whole genome sequence [Website] [Paper]
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