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Old 01-09-2012, 01:26 PM   #3
brachysclereid
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Location: California

Join Date: Feb 2011
Posts: 32
Default who coined RNAseq? RNAseq as an alignment first approach only

Yes. The fact that RNA-seq stands for RNA-SEQuencing was not lost to me. However, initially the high depth sequencing reads were aligned to a reference genome and thus RNA-seq became synonymous with an alignment first approach. It was only later that de novo assembly of RNA-seq data was performed routinely. At least from my perspective.
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