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Old 02-11-2013, 01:27 PM   #1
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Location: CO

Join Date: Feb 2013
Posts: 1
Default Duplicates and targeted sequencing

I am trying to analyze data that sequenced targeted regions of the genome (about 500 Mb in total). In the GATK pipeline it suggests marking duplicates/removing duplicates. Is this important to do with targeted sequencing? Wouldn't you expect duplicates because of the experimental design? Thanks!
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