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Old 10-01-2013, 07:15 PM   #3
Location: Russia, Irkutsk

Join Date: Feb 2011
Posts: 40

They are more or less overlapping, though sometimes only by a few AA. The amount of transmembrane domains is also the same in all estimates. This is actually all I need (how many domains there are and whether they are before or after a certain site).
But the general question still remains: if I want to reliably estimate domains having only some protein sequences, say, from genome we are annotating, what tool should I use and what parameters and how should be optimised?
A_Morozov is offline   Reply With Quote